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Clarity in Trials, Confidence in Decisions
Clarity in Trials, Confidence in Decisions
Clascoterone (WINLEVI) — Drug Profile | TrialistMD TRIALISTMD.COM DERMATOLOGY · ANDROGEN RECEPTOR INHIBITOR Androgen Receptor Inhibitor · NME · Dermatology · NDA 213433 Clascoterone WINLEVI™ · Cassiopea SpA First-in-class topical androgen receptor inhibitor (cortexolone-17α-propionate) that competes with dihydrotestosterone for binding…
Dupilumab — TrialistMD Drug Profile TRIALISTMD · DRUG INTELLIGENCE DERMATOLOGY IL-4Rα Antagonist · Monoclonal Antibody · BLA 761055 dupilumab DUPIXENT® Recombinant fully human IgG4 monoclonal antibody targeting the IL-4Rα subunit, blocking both IL-4 and IL-13 signaling via Type I and…
Risankizumab (SKYRIZI) — Drug Profile | TrialistMD TRIALISTMD.COM DRUG PROFILE IL-23 Antagonist · Humanized IgG1 mAb · Dermatology Risankizumab SKYRIZI™ · AbbVie Inc. Humanized IgG1 monoclonal antibody that selectively binds the p19 subunit of IL-23, blocking its interaction with the…
Brodalumab (SILIQ) — Drug Profile | TrialistMD TRIALISTMD.COM DRUG PROFILE IL-17RA Antagonist · Human Monoclonal Antibody IgG2κ · Dermatology brodalumab SILIQ™ · Valeant Pharmaceuticals North America LLC Fully human IgG2κ monoclonal antibody that selectively binds to interleukin-17 receptor A (IL-17RA),…
Tildrakizumab (ILUMYA) — Drug Profile | TrialistMD TRIALISTMD.COM DRUG PROFILE IL-23 Antagonist · Humanized mAb · Dermatology · BLA 761067 tildrakizumab ILUMYA™ · tildrakizumab-asmn · Merck Sharp & Dohme Corp. Humanized IgG1/κ monoclonal antibody selectively binding the p19 subunit of…
Guselkumab (TREMFYA) — Drug Profile | TrialistMD TRIALISTMD.COM DRUG PROFILE IL-23 p19 Inhibitor · Monoclonal Antibody · Dermatology Guselkumab TREMFYA™ · Janssen Biotech, Inc. Human IgG1λ monoclonal antibody selectively binding the p19 subunit of IL-23, preventing IL-23/IL-23R interaction and downstream…
crisaborole (EUCRISA) — Drug Profile | TrialistMD TRIALISTMD.COM DERMATOLOGY · PDE-4 INHIBITOR PDE-4 Inhibitor · Topical Small Molecule · Atopic Dermatitis · NDA 207695 crisaborole EUCRISA™ · Anacor Pharmaceuticals (Pfizer) First-in-class boron-based topical phosphodiesterase-4 (PDE-4) inhibitor. Inhibits cAMP degradation in…
Lebrikizumab (EBGLYSS) — Drug Profile | TrialistMD TRIALISTMD.COM DRUG PROFILE Anti-IL-13 Monoclonal Antibody · Type 2 Biologic · Atopic Dermatitis lebrikizumab EBGLYSS® · Eli Lilly and Company An IgG4 monoclonal antibody that binds IL-13 with high affinity and slow off-rate,…
Tapinarof (VTAMA) — Drug Profile | TrialistMD TRIALISTMD.COM DRUG PROFILE AhR Agonist · Small Molecule · Dermatology · Plaque Psoriasis Tapinarof VTAMA™ · Dermavant Sciences Inc. Tapinarof is a first-in-class aryl hydrocarbon receptor (AhR) agonist for topical use. Applied once…
Tralokinumab (ADBRY) — Drug Profile | TrialistMD TRIALISTMD.COM DRUG PROFILE IL-13 Antagonist · IgG4 mAb · Dermatology · Atopic Dermatitis Tralokinumab-ldrm ADBRY™ · LEO Pharma A/S A fully human IgG4 monoclonal antibody that selectively neutralizes interleukin-13 (IL-13), a key Th2…